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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
26.97
Human Site:
S290
Identified Species:
42.38
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
S290
Y
E
E
A
R
K
F
S
Y
R
S
R
V
R
P
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
S288
Y
E
E
A
R
K
F
S
Y
R
S
R
V
R
P
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
S540
Y
E
E
A
R
K
F
S
Y
R
S
R
V
R
P
Dog
Lupus familis
XP_861268
662
73195
S290
Y
E
E
A
R
K
F
S
Y
R
S
R
V
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
S290
Y
E
E
A
R
K
F
S
Y
R
S
R
V
R
P
Rat
Rattus norvegicus
NP_001102328
659
72976
S288
Y
E
E
A
R
K
F
S
Y
R
S
R
V
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
A276
Y
E
E
A
R
K
F
A
Y
R
S
R
V
R
P
Chicken
Gallus gallus
NP_001025971
651
72031
A282
Y
E
E
A
R
K
F
A
Y
R
S
R
V
R
P
Frog
Xenopus laevis
P24346
697
77284
A331
Y
E
E
A
R
K
F
A
Y
R
S
R
V
R
P
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
S322
Y
D
E
A
R
K
F
S
Y
R
S
H
V
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
A402
F
E
E
A
K
K
F
A
Y
R
S
R
M
R
P
Honey Bee
Apis mellifera
XP_391829
701
78642
A328
Y
D
E
A
R
K
F
A
Y
R
S
R
M
R
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
D276
R
E
L
E
R
G
V
D
I
L
V
A
T
P
G
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
V271
S
W
V
R
P
C
V
V
Y
G
G
A
P
I
G
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
A303
Y
D
E
A
R
K
F
A
Y
R
S
W
V
R
P
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
73.3
80
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
80
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
87
0
0
0
40
0
0
0
14
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
74
87
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
87
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
7
7
0
0
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
87
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
87
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
7
87
0
0
0
0
87
0
74
0
87
0
% R
% Ser:
7
0
0
0
0
0
0
47
0
0
87
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
7
0
0
0
14
7
0
0
7
0
74
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
80
0
0
0
0
0
0
0
94
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _